Sunday, November 27, 2016

Iridocorneal Endothelial Syndrome (ICE) Syndrome


Our inaugural post comes from Brett Levinson, MD of Specialized Eye Care. The images are of a patient in her 30s who noted a triangular shaped left pupil for 2 years which is getting worse. On clinical exam, she has three areas of iris atrophy. Cornea exam was normal. On OCT, there is complete loss of the iris stroma and the residual iris pigment epithelium, and the anterior synechae.


The images are consistent with Essential iris atrophy. This diagnosis is one of three iridocorneal endothelial (ICE) syndromes. Changes affect one eye. Attachments of the iris to the cornea (anterior synechiae) can lead to secondary glaucoma with closure of the angle.

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